Replication and mediation of the association between the metabolome and clinical markers of metabolic health in an adolescent cohort study
Abstract Metabolomics-derived metabolites (henceforth metabolites) may mediate the relationship between modifiable risk factors and clinical biomarkers of metabolic health (henceforth clinical biomarkers).We set out to study the associations of metabolites with clinical biomarkers and a potential mediation effect in a population of young adults.Fir